The current version of GADMA (greater than 2.0.0) supports Python3 only. Older versions supported Python 2 as well but not any more.

Below we hightlight GADMA dependencies. All of them could be easily installed using requirements files which are specified in the brackets before lists. To install dependencies from requerement file run:

$ pip -r requirements_file

GADMA requires the following dependencies (requirements/minimal.txt):

  • Python3
  • NumPy (>= 1.2.0)
  • Scipy (>= 0.6.0)
  • ruamel.yaml
  • dadi (>= 1.7.0)
  • moments (>= 1.0.0)
  • momi
  • moments.LD (manual installation of moments with –ld-extension flag)
  • nlopt (for dadi)
  • Cython (for moments)
  • mpmath (for moments)

To draw demographic models one should also install the following packages (requirements/minimal.txt):

  • matplotlib (>= 0.98.1)
  • Pillow (>= 4.2.1) - optional
  • moments (>= 1.0.0)

To use demes engine to draw models (requirements/engines.txt):

  • demes
  • demesdraw

To calculate confidence intervals one should install (requirements/minimal.txt):

  • pandas

To run Bayesian optimization smac of specified version is requered (requirements/bayes_opt.txt):

  • scikit-optimize
  • configspace
  • smac (==0.13.1)


momi package sometimes is not installed correctly for Windows and MacOS. If momi is not available please install it manually following the installation instructions in momi’s manual.


momentsLD - the extension of moments, should be installed manually following the installation instructions in moments’s manual.

Getting help for engine installation

If there are some troubles installing the engine, please, first of all check the table below for the ability to install this engine on your system. You are always welcome to open an issue on GitHub for getting help.

GADMA has automatic tests on GitHUb for engines on different systems (Linux, Windows, MacOS). The following table indicates (according to our tests) if engine could be installed on specified system:

Feature dadi moments momi momentsLD

Installing the latest release

The latest release of GADMA is easily installed via pip or conda (bioconda):

$ pip install gadma


$ conda install -c bioconda gadma


Installation via pip and conda will not install the moments library. To install it one should run:

$ pip install git+


$ conda install -c bioconda moments

Manual installation

Some features are added to the GADMA project but are not released yet. One can install GADMA directly from the repository.

First clone the repository:

$ git clone
$ cd GADMA

Dependencies could be installed either automatically or manually.

Automatic mode

One could install everything with the install script:

$ ./install

Full-manual mode

Install dependencies manually:

  • NumPy
    $ pip install numpy
  • Scipy
    $ pip install scipy
  • ruamel.yaml
    $ pip install ruamel.yaml
  • dadi, nlopt
    $ pip install dadi
  • moments, mpmath, Cython
    $ pip install --upgrade Cython
    $ pip install mpmath
    $ pip install git+
  • momi
    $ pip install momi
  • matplotlib
    $ pip install matplotlib
  • Pillow
    $ pip install Pillow
  • pandas
    $ pip install pandas
  1. Install GADMA
    $ pip install .

Verifying installation

To verify the installation, run:

$ gadma --test

If the installation was successful, one will find the following information at the end:

--Finish pipeline--

--Test passed correctly--
Thank you for using GADMA!